SCHEMBL1946705

SCHEMBL1946705

CC(C)CCNC(=O)c1cc(NC(=O)C(C)(C)C)cc(NC(=O)C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ RAB9A P51151 3/20 0.47
▸ NPC1 O15118 2/20 0.47
▸ GAA P10253 2/20 0.47
▸ LMNA P02545 1/20 0.46
▸ NPSR1 Q6W5P4 1/20 0.43
▸ NAMPT P43490 5/20 0.43
▸ HTT P42858 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914672 0.90 MEN1 (0.42) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL28892112 0.82 SMN1; SMN2 (0.49) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL1946573 0.81 SMN1; SMN2 (0.48) SMN1; SMN2RAB9ANPC1GAALMNA
SCHEMBL1947969 0.81 SMN1; SMN2 (0.50) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL31477865 0.80 SMN1; SMN2 (0.53) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL1561293 0.79 SMN1; SMN2 (0.62) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL2915919 0.79 SMN1; SMN2 (0.36) SMN1; SMN2RAB9ANPC1GAALMNA
SCHEMBL13178707 0.79 SMN1; SMN2 (0.47) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL1950785 0.77 MEN1 (0.54) MEN1KMT2ASMN1; SMN2RAB9ANPC1
SCHEMBL27976289 0.77 ALDH1A1 (0.46) MEN1KMT2ASMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 — — EP claimed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 — — EP claimed
EP-2510047-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2012-10-17 — — EP claimed
WO-2011071718-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2011-06-16 — — WO claimed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 — — US claimed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 — — US claimed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 — — US claimed
JP-2006518402-A — — 2006-08-10 — — JP claimed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 — — EP claimed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 — — WO claimed
CN-115556441-B Decorative film and method for producing decorative molded article using same 日本聚丙烯株式会社 2025-04-11 — — CN disclosed
US-20200384678-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2020-12-10 — — US disclosed
EP-3715092-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2020-09-30 — — EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 — — EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 — — EP disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 — — US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 — — US disclosed
WO-2007068766-A1 MONO- AND MULTI-LAYER BLOWN FILMS CIBA HOLDING INC. (CH) 2007-06-21 — — WO disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 — — EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 — — WO disclosed
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