SCHEMBL194674

SCHEMBL194674

[CH]1CCCCCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4588 1.00
SCHEMBL1699085 1.00
SCHEMBL574734 1.00 ALDH1A1 (0.33)
SCHEMBL1238545 0.97 ALDH1A1 (0.32)
SCHEMBL9421 0.97
Hydrochloric Acid SCHEMBL7289100 0.93
Hydrochloric Acid SCHEMBL7715636 0.83
SCHEMBL7413992 0.75
SCHEMBL237047 0.73
SCHEMBL25134064 0.69 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3788042-A1 BCL-2 INHIBITORS BeiGene, Ltd. (KY) 2021-03-10 EP claimed
EP-3505171-A1 BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND Mitsubishi Tanabe Pharma Corporation (JP) 2019-07-03 EP claimed
US-20190185479-A1 BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND MITSUBISHI TANABE PHARMA CORPORATION (JP) 2019-06-20 US claimed
EP-2589592-B1 NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF FUJIFILM CORP (JP) 2018-08-22 EP claimed
EP-2167489-B1 PYRIMIDINE DERIVATIVES USEFUL AS RAF KINASE INHIBITORS SUNESIS PHARMACEUTICALS INC (US) 2017-05-03 EP claimed
US-8895585-B2 Nicotinamide derivative or salt thereof FUJIFILM CORPORATION (JP) 2014-11-25 US claimed
US-8809371-B2 2014-08-19 US claimed
US-8802657-B2 Compounds useful as Raf kinase inhibitors MILLENNIUM PHARMACEUTICALS, INC. (US) 2014-08-12 US claimed
US-8772320-B2 2014-07-08 US claimed
US-20130065858-A1 COMPOUNDS USEFUL AS RAF KINASE INHIBITORS SUNESIS PHARMACEUTICALS, INC. (US) 2013-03-14 US claimed
EP-0124216-A1 C-20- and C-23-modified macrolide derivatives ELI LILLY AND COMPANY (US) 1984-11-07 EP claimed
US-4468511-A C-20- And C-23-Modified macrolide derivatives ELI LILLY AND COMPANY (US) 1984-08-28 US claimed
US-4447432-A BACTERICIDES FARMITALIA CARLO ERBA S.P.A. (IT) 1984-05-08 US claimed
EP-0103465-A1 20-Amino macrolide derivatives ELI LILLY AND COMPANY (US) 1984-03-21 EP claimed
EP-0102239-A1 Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics SANKYO COMPANY LIMITED (JP) 1984-03-07 EP claimed
US-4423047-A INHIBITING ABNORMAL CELL PROLIFERATION NYEGAARD & CO. A/S (NO) 1983-12-27 US claimed
US-4327096-A OBTAINED BY REACTING 3-AMINO RIFAMYCIN WITH A CHLOROFORMIMINO CHLORIDE FARMITALIA CARLO ERBA S.P.A. (IT) 1982-04-27 US claimed
US-4287338-A Sulfooxy-pyrimidinium, -pyridinium, and -triazinium hydroxide inner salts THE UPJOHN COMPANY (US) 1981-09-01 US claimed
US-4259333-A ANTIBIOTICS, BACTERICIDES LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1981-03-31 US claimed
US-4139626-A FUNGICIDES SYNTEX (U.S.A.) INC. (US) 1979-02-13 US claimed