Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.72 |
| ▸ | RELA | Q04206 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | JUN | P05412 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | CDC25A | P30304 | 1/20 | 0.65 |
| ▸ | CDC25C | P30307 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7185011 | 0.91 | ABCG2 (0.97) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL7185006 | 0.91 | ABCG2 (0.97) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL28261935 | 0.90 | TNFRSF1A (0.82) | ABCG2KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL28263078 | 0.88 | ABCG2 (0.80) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL7188211 | 0.87 | ABCG2 (0.79) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL7188219 | 0.87 | ABCG2 (0.79) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL5424613 | 0.87 | ABCG2 (0.79) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL6352780 | 0.87 | ABCG2 (0.89) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL30307319 | 0.87 | ABCG2 (0.89) | ABCG2KDM4ELMNAMAPTATM | |
| SCHEMBL5424620 | 0.87 | ABCG2 (0.79) | ABCG2KDM4ELMNAMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108904481-A | O-hydroxylate chalcone analog is preparing the application in anti-oxidation medicine | 温州医科大学 | 2018-11-30 | — | — | CN | disclosed |
| EP-3278797-A1 | ANTIALLERGIC AGENT | Tohoku University (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-20170304236-A1 | ANTIALLERGIC AGENT | TOHOKU UNIVERSITY (JP) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304236-A1 | ANTIALLERGIC AGENT | HRH2, HRH4, HRH1 | ABCG2 2921/4885KDM4E 2907/4885LMNA 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.