Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | JUN | P05412 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.60 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424613 | 1.00 | ABCG2 (0.79) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL5433441 | 0.88 | ABCG2 (0.73) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL5433445 | 0.88 | ABCG2 (0.73) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL19468567 | 0.87 | ABCG2 (0.86) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL7185011 | 0.87 | ABCG2 (0.97) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL7185006 | 0.87 | ABCG2 (0.97) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL6352783 | 0.86 | ABCG2 (0.89) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL6352780 | 0.86 | ABCG2 (0.89) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL7180833 | 0.84 | ABCG2 (0.86) | ABCG2MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL7180829 | 0.84 | ABCG2 (0.86) | ABCG2MAPTSMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132135-A1 | ESTROGEN RECEPTOR ALPHA COLIGANDS, AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-03 | — | — | WO | disclosed |
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | EASTMAN CHEMICAL COMPANY | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254859-A1 | Compounds exhibiting efflux inhibitor activity and composition and uses thereof | ABCC4, NCOA4, NR4A3 | ABCG2 5/4885MAPT 4566/4885SMN1; SMN2 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.