Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468569 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19468574 | 0.92 | SMN1; SMN2 (0.70) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19468578 | 0.87 | SMN1; SMN2 (0.82) | SMN1; SMN2MTNR1AMTNR1BMAPTKDM4E | |
| SCHEMBL19468566 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19468576 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19468570 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2MTNR1AMTNR1BMAPTKDM4E | |
| SCHEMBL7194877 | 0.76 | PDE4A (0.81) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18183442 | 0.76 | MTNR1B (0.84) | MTNR1AMTNR1B | |
| SCHEMBL7194872 | 0.76 | PDE4A (0.81) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31467939 | 0.75 | SMN1; SMN2 (0.54) | SMN1; SMN2ABCG2MTNR1AMTNR1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3278797-A1 | ANTIALLERGIC AGENT | Tohoku University (JP) | 2018-02-07 | — | — | EP | disclosed |
| US-20170304236-A1 | ANTIALLERGIC AGENT | TOHOKU UNIVERSITY (JP) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304236-A1 | ANTIALLERGIC AGENT | HRH2, HRH4, HRH1 | SMN1; SMN2 3336/4885PDE4A 845/4885PDE4B 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.