Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 10/20 | 0.67 |
| ▸ | CDC7 | O00311 | 1/20 | 0.65 |
| ▸ | PLK4 | O00444 | 1/20 | 0.65 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.65 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.65 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.65 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.65 |
| ▸ | ABL1 | P00519 | 1/20 | 0.65 |
| ▸ | PRKCG | P05129 | 1/20 | 0.65 |
| ▸ | INSR | P06213 | 1/20 | 0.65 |
| ▸ | FYN | P06241 | 1/20 | 0.65 |
| ▸ | RET | P07949 | 1/20 | 0.65 |
| ▸ | IGF1R | P08069 | 1/20 | 0.65 |
| ▸ | ROS1 | P08922 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19472596 | 0.84 | MAPT (0.83) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19472721 | 0.83 | MAPT (0.81) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19472582 | 0.82 | MAPT (0.79) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19472586 | 0.82 | MAPT (1.00) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19478603 | 0.81 | MAPT (0.81) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19478508 | 0.81 | MAPT (0.81) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19472580 | 0.81 | CDC7 (0.80) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19472585 | 0.81 | HPGD (1.00) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19472806 | 0.81 | CDC7 (0.69) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL19472804 | 0.81 | MAPT (0.73) | MAPTMEN1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298056-A1 | SMALL MOLECULE INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298056-A1 | SMALL MOLECULE INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | CD4, CCR5, CCR1 | MAPT 3451/4885MEN1 4090/4885KMT2A 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.