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Sugi Predict / Compounds / SCHEMBL19473791

SCHEMBL19473791

SCHEMBL19473791

CCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)C(Cc2c[nH]cn2)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(C)=O)CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 20/20 0.66
▸ MC3R P41968 9/20 0.66
▸ MC5R P33032 6/20 0.66
▸ MC1R Q01726 5/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19473991 1.00 MC4R (0.66) MC4RMC3RMC5RMC1R
SCHEMBL13063946 1.00 MC4R (0.66) MC4RMC3RMC5RMC1R
SCHEMBL10307917 1.00 MC4R (0.66) MC4RMC3RMC5RMC1R
SCHEMBL19473989 1.00 MC4R (0.66) MC4RMC3RMC5RMC1R
Melatonan SCHEMBL29473785 0.98 MC4R (0.67) MC4RMC3RMC5RMC1R
SCHEMBL19473806 0.98 MC4R (0.64) MC4RMC3RMC5RMC1R
SCHEMBL13063933 0.98 MC4R (0.64) MC4RMC3RMC5RMC1R
SCHEMBL10307923 0.98 MC4R (0.64) MC4RMC3RMC5RMC1R
SCHEMBL10307921 0.98 MC4R (0.64) MC4RMC3RMC5RMC1R
SCHEMBL13063966 0.98 MC4R (0.64) MC4RMC3RMC5RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440227-B1 MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES PALATIN TECHNOLOGIES INC (US) 2017-10-18 — — EP disclosed
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