Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.67 |
| ▸ | MC3R | P41968 | 9/20 | 0.67 |
| ▸ | MC5R | P33032 | 6/20 | 0.67 |
| ▸ | MC1R | Q01726 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19473991 | 0.98 | MC4R (0.66) | MC4RMC3RMC5RMC1R | |
| SCHEMBL10307917 | 0.98 | MC4R (0.66) | MC4RMC3RMC5RMC1R | |
| SCHEMBL13063946 | 0.98 | MC4R (0.66) | MC4RMC3RMC5RMC1R | |
| SCHEMBL19473791 | 0.98 | MC4R (0.66) | MC4RMC3RMC5RMC1R | |
| SCHEMBL19473989 | 0.98 | MC4R (0.66) | MC4RMC3RMC5RMC1R | |
| SCHEMBL19473806 | 0.98 | MC4R (0.64) | MC4RMC3RMC5RMC1R | |
| SCHEMBL13063933 | 0.98 | MC4R (0.64) | MC4RMC3RMC5RMC1R | |
| SCHEMBL10307923 | 0.98 | MC4R (0.64) | MC4RMC3RMC5RMC1R | |
| SCHEMBL10307921 | 0.98 | MC4R (0.64) | MC4RMC3RMC5RMC1R | |
| SCHEMBL10307956 | 0.98 | MC4R (0.64) | MC4RMC3RMC5RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281919-A1 | pH-SENSITIVE CYCLIC PEPTIDES | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2022-09-08 | — | — | US | disclosed |
| US-11274126-B2 | pH-sensitive cyclic peptides | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2022-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274126-B2 | pH-sensitive cyclic peptides | VIP, PHLPP1, PHLPP2 | MC4R 2841/4885MC3R 2388/4885MC5R 3164/4885 |
| US-20220281919-A1 | pH-SENSITIVE CYCLIC PEPTIDES | VIP, PHLPP1, PHLPP2 | MC4R 2841/4885MC3R 2388/4885MC5R 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.