SCHEMBL19474338

SCHEMBL19474338

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccc5)cc4)nc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7ccc(-c8ccc(-c9cccc(-c%10ccc(-c%11nc(-c%12ccccc%12)nc(-n%12c%13ccccc%13c%13ccc%14c%15ccccc%15n(-c%15ccc(-c%16ccccc%16)cc%15)c%14c%13%12)n%11)cc%10)c9)cc8)cc7)c6c54)n3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NR3C1 P04150 1/20 0.35
HDAC4 P56524 1/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
RXRA P19793 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
HSP90AA1 P07900 1/20 0.33
AVPR1A P37288 1/20 0.33
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16521294 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL16521296 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL26059080 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL27050451 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24691494 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24691501 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL26059052 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24549519 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL19474386 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24691488 0.99 ATM (0.38) KDM4EATML3MBTL1NR3C1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2866273-B1 Organic electrolumiescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-10-18 EP disclosed