SCHEMBL26059080

SCHEMBL26059080

c1ccc(-c2cccc(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccc(-n6c7ccccc7c7ccc8c9ccccc9n(-c9nc(-c%10ccccc%10)nc(-c%10ccccc%10)n9)c8c76)cc5)n4)cc3)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NR3C1 P04150 1/20 0.35
HDAC4 P56524 1/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
MAPT P10636 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
RXRA P19793 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
LMNA P02545 1/20 0.33
GLA P06280 1/20 0.33
HSP90AA1 P07900 1/20 0.33
AVPR1A P37288 1/20 0.33
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16521294 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL16521296 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL27050451 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24691494 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL19474338 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24691501 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL26059052 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24549519 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL19474386 1.00 KDM4E (0.39) KDM4EATML3MBTL1NR3C1HDAC4
SCHEMBL24691488 0.99 ATM (0.38) KDM4EATML3MBTL1NR3C1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363190-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-09 US disclosed
US-20230363190-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-09 US disclosed
US-20230276704-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-08-31 US disclosed
US-20230276704-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-08-31 US disclosed
EP-4235831-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-08-30 EP disclosed
EP-4234556-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276704-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT ETV6, IKZF2, EML4 KDM4E 380/4885ATM 4641/4885L3MBTL1 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.