Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707251 | 0.86 | HAO1 (0.46) | PDE1CHAO1PRMT5ERCC1ERCC4 | |
| SCHEMBL31729098 | 0.78 | SMN1; SMN2 (0.62) | MEN1KMT2AFASN | |
| SCHEMBL15825245 | 0.78 | KDM4E (0.55) | MEN1KMT2APRMT5WDR77 | |
| SCHEMBL13113212 | 0.77 | HTR2A (0.59) | PDE1CMEN1KMT2AERCC1ERCC4 | |
| SCHEMBL29503149 | 0.76 | AR (0.55) | PDE1CKMT2AERCC1ERCC4FASN | |
| SCHEMBL19691125 | 0.76 | AR (0.55) | PDE1CKMT2AERCC1ERCC4FASN | |
| SCHEMBL26699112 | 0.75 | CYP2A6 (0.46) | MEN1KMT2A | |
| SCHEMBL30444577 | 0.75 | NOTUM (0.42) | PDE1CHAO1PRMT5ERCC1ERCC4 | |
| SCHEMBL17473919 | 0.74 | HTR2A (0.42) | PDE1CHAO1PRMT5ERCC1ERCC4 | |
| SCHEMBL30006720 | 0.74 | PDE1C (0.48) | PDE1CERCC1ERCC4KMOVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111479805-A | Therapeutic indazoles | 罗格斯新泽西州立大学 | 2020-07-31 | — | — | CN | disclosed |
| WO-2017184589-A1 | A VERSATILE LIGAND FOR PALLADIUM-CATALYZED META-C-H FUNCTIONALIZATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-26 | — | — | WO | disclosed |