Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 17/20 | 0.80 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10241828 | 0.92 | CDK9 (0.67) | CDK9CCNT1KDM4EALDH1A1GAA | |
| SCHEMBL10241727 | 0.92 | CDK9 (0.67) | CDK9CCNT1KDM4EALDH1A1GAA | |
| SCHEMBL1948930 | 0.89 | CDK9 (1.00) | CDK9CCNT1 | |
| SCHEMBL10285651 | 0.88 | CCNT1 (0.62) | CDK9CCNT1 | |
| SCHEMBL10241738 | 0.87 | CDK9 (0.60) | CDK9CCNT1 | |
| SCHEMBL10241715 | 0.87 | CDK9 (0.60) | CDK9CCNT1 | |
| SCHEMBL1946333 | 0.85 | CCNT1 (0.58) | CDK9CCNT1 | |
| SCHEMBL10285649 | 0.85 | CCNT1 (0.58) | CDK9CCNT1 | |
| SCHEMBL1462646 | 0.85 | CCNT1 (0.58) | CDK9CCNT1 | |
| SCHEMBL1946308 | 0.85 | CCNT1 (0.58) | CDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130380-A1 | Heteroaryl Kinase Inhibitors | NOVARTIS AG (CH) | 2011-06-02 | — | — | US | disclosed |
| US-20110130380-A1 | Heteroaryl Kinase Inhibitors | NOVARTIS AG (CH) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130380-A1 | Heteroaryl Kinase Inhibitors | CDK2, CDK1, CDKL1 | CDK9 5/4885CCNT1 47/4885KDM4E 854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.