Eperisone

Eperisone

SCHEMBL194769

CCc1ccc(C(=O)C(C)CN2CCCCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 1.00
CHRM2 P08172 2/20 1.00
ADRA2B P18089 2/20 1.00
DRD3 P35462 2/20 1.00
SIGMAR1 Q99720 2/20 1.00
CYP2D6 P10635 1/20 1.00
ADRA2C P18825 1/20 1.00
CHRM3 P20309 1/20 1.00
OPRD1 P41143 1/20 1.00
KCNH2 Q12809 1/20 1.00
ALDH1A1 P00352 4/20 0.72
LMNA P02545 4/20 0.72
SLC6A4 P31645 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
USP2 O75604 1/20 0.48
ALOX15 P16050 1/20 0.48
NTSR1 P30989 1/20 0.47
MITF O75030 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
RAB9A P51151 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eperisone SCHEMBL1331682 1.00 HRH3 (1.00) HRH3CHRM2ADRA2BDRD3SIGMAR1
Eperisone SCHEMBL218337 0.99 HRH3 (0.97) HRH3CHRM2ADRA2BDRD3SIGMAR1
Inaperisone SCHEMBL250427 0.98 HRH3 (0.97) HRH3CHRM2ADRA2BDRD3SIGMAR1
Inaperisone SCHEMBL3990438 0.97 CHRM2 (0.94) HRH3CHRM2ADRA2BDRD3SIGMAR1
Inaperisone SCHEMBL1650087 0.96 HRH3 (0.92) HRH3CHRM2ADRA2BDRD3SIGMAR1
Eperisone SCHEMBL2491287 0.93 HRH3 (0.87) HRH3CHRM2ADRA2BDRD3SIGMAR1
Eperisone SCHEMBL1329969 0.93 HRH3 (0.87) HRH3CHRM2ADRA2BDRD3SIGMAR1
Eperisone SCHEMBL1331476 0.92 HRH3 (0.85) HRH3CHRM2ADRA2BDRD3SIGMAR1
Eperisone SCHEMBL2489151 0.92 HRH3 (0.85) HRH3CHRM2ADRA2BDRD3SIGMAR1
Eperisone SCHEMBL1331479 0.92 HRH3 (0.85) HRH3CHRM2ADRA2BDRD3SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-119792221-A Pharmaceutical composition and preparation method and application thereof 江苏吴中医药集团有限公司 2025-04-11 CN claimed
WO-2025062440-A1 TOPICAL NANO-DISPERSION COMPOSITIONS AND THEIR PREPARATION THEREOF PULSE PHARMACEUTICALS PVT. LTD (IN) 2025-03-27 WO claimed
CN-119330913-A Preparation method of eperisone hydrochloride 康普药业股份有限公司 2025-01-21 CN claimed
CN-118593492-A Application of eperisone in treating pulmonary fibrosis caused by silicon dust 山西医科大学 2024-09-06 CN claimed
CN-118436591-A External preparation of betahistine and application thereof 山东序列生物科技有限公司 2024-08-06 CN claimed
CN-118436593-A External preparation of eperisone and application thereof 山东序列生物科技有限公司 2024-08-06 CN claimed
CN-118436592-A Dantrolin sodium external preparation and preparation method and application thereof 山东序列生物科技有限公司 2024-08-06 CN claimed
CN-117209455-B Refining and purifying method of eperisone hydrochloride 北京沃邦医药科技有限公司 2024-05-28 CN claimed
CN-117209455-A Refining and purifying method of eperisone hydrochloride 北京沃邦医药科技有限公司 2023-12-12 CN claimed
US-5073375-A Monoglyceride or lactic acid ester SANSHO CO., LTD. (JP) 1991-12-17 US claimed
CN-1056055-A Eperisone and mydocalm preparation that percutaneous absorbs SEIKISUI CHEMICAL CO LTD (JP) 1991-11-13 CN claimed
EP-0454089-A1 Percutaneously absorbable eperisone or tolperisone preparation SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-10-30 EP claimed
US-5059427-A PHARMACEUTICAL PREPARATION FOR PERCUTANEOUS ADMINISTRATION CONTAINING EPERISONE OR TOLPERISONE OR SALT THEREOF SANSHO CO., LTD. (JP) 1991-10-22 US claimed
US-5002958-A P-Ethyl-2-Methyl-3-Piperidinopropiophenone EISAI CO., LTD. (JP) 1991-03-26 US claimed
EP-0295411-B1 PHARMACEUTICAL PREPARATION FOR PERCUTANEOUS ADMINISTRATION CONTAINING EPERISONE OR TOLPERISONE OR A SALT THEREOF Sansho Co., Ltd. (JP) 1990-09-05 EP claimed
US-4912116-A Propiophenone derivatives for treatment of pollakiuria (frequency urination) HOKURIKU PHARMACEUTICAL CO., LTD. (JP) 1990-03-27 US claimed
EP-0295411-A1 Pharmaceutical preparation for percutaneous administration containing eperisone or tolperisone or a salt thereof Sansho Co., Ltd. (JP) 1988-12-21 EP claimed
US-4181803-A 4'-SUBSTITUTED-2-METHYL-3-PIPERIDINO-PROPIOPHENONES; ANTISPASMODIC AGENTS, MUSCLE RELAXANTS EISAI CO., LTD. (JP) 1980-01-01 US claimed
US-3995047-A Propiophenone derivatives in the treatment of pathological muscular conditions EISAI CO., LTD. (JA) 1976-11-30 US claimed