Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573225 | 0.81 | KDM4E (0.63) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL3581788 | 0.80 | KDM4E (0.56) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL1238023 | 0.80 | KDM4E (0.56) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL1244846 | 0.78 | KDM4E (0.54) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL3023628 | 0.78 | KDM4E (0.56) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL1244714 | 0.77 | KDM4E (0.59) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL8255791 | 0.77 | KDM4E (0.59) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL29238062 | 0.77 | KDM4E (0.48) | KDM4EPKMHPGDEPHX1KEAP1 | |
| SCHEMBL627965 | 0.76 | KDM4E (0.60) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL24411175 | 0.76 | KDM4E (0.54) | KDM4EPKMHPGDRECQLEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017181177-A1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | Epizyme, Inc. (US) | 2017-10-19 | — | — | WO | disclosed |