Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30407016 | 0.86 | GPR119 (0.49) | KDM4EPKMKEAP1NFE2L2EPHX1 | |
| SCHEMBL13509914 | 0.81 | HPGD (0.47) | KDM4EPKMTGFBR1KEAP1NFE2L2 | |
| SCHEMBL5573225 | 0.80 | KDM4E (0.63) | KDM4EPKMTGFBR1GLSEPHX1 | |
| SCHEMBL1238023 | 0.79 | KDM4E (0.56) | KDM4EPKMTGFBR1GLSEPHX1 | |
| SCHEMBL3581788 | 0.79 | KDM4E (0.56) | KDM4EPKMTGFBR1GLSEPHX1 | |
| SCHEMBL1244846 | 0.77 | KDM4E (0.54) | KDM4EPKMTGFBR1GLSEPHX1 | |
| SCHEMBL19477449 | 0.77 | KDM4E (0.49) | KDM4EPKMTGFBR1KEAP1NFE2L2 | |
| SCHEMBL1244714 | 0.76 | KDM4E (0.59) | KDM4EPKMTGFBR1GLSEPHX1 | |
| SCHEMBL13694467 | 0.76 | NR1H2 (0.43) | KDM4EPKMTGFBR1KEAP1NFE2L2 | |
| SCHEMBL14678793 | 0.76 | NR1H2 (0.43) | KDM4EPKMTGFBR1KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239928-A | Fibroblast activation protein affinity compound and radioactive marker thereof | 南京思锘新药研发有限公司 | 2024-06-25 | — | — | CN | disclosed |