SCHEMBL1947748

SCHEMBL1947748

O=C(Nc1cc(NC(=O)C2CC2)cc(NC(=O)C2CC2)c1)C1CC1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.63
MEN1 O00255 5/20 0.62
KMT2A Q03164 5/20 0.62
LMNA P02545 5/20 0.62
NPSR1 Q6W5P4 1/20 0.62
NAMPT P43490 2/20 0.61
GAA P10253 3/20 0.57
MAPT P10636 3/20 0.57
GFER P55789 1/20 0.57
HPGD P15428 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
HTT P42858 2/20 0.55
USP2 O75604 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
PTPN1 P18031 1/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
ALDH1A1 P00352 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1948869 0.91 NPSR1 (0.75) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL25522867 0.89 HSD17B10 (0.54) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL19327751 0.89 HSD17B10 (0.59) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL19327631 0.89 HSD17B10 (0.59) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL19327640 0.89 HSD17B10 (0.59) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL19327668 0.89 HSD17B10 (0.59) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL19327630 0.89 HSD17B10 (0.59) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL1946708 0.89 NPSR1 (0.72) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL18154026 0.85 MEN1 (0.86) HSD17B10MEN1KMT2ALMNANPSR1
SCHEMBL19327629 0.84 HSD17B10 (0.54) HSD17B10MEN1KMT2ALMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
EP-2510047-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2012-10-17 EP disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
WO-2011071718-A2 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2011-06-16 WO disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed