SCHEMBL19327751

SCHEMBL19327751

C[C@H]1CC[C@H](C(=O)Nc2cc(NC(=O)[C@H]3CC[C@H](C)CC3)cc(NC(=O)[C@H]3CC[C@@H](C)CC3)c2)CC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.59
LMNA P02545 4/20 0.58
NPSR1 Q6W5P4 2/20 0.58
NAMPT P43490 1/20 0.56
F2 P00734 1/20 0.55
PLG P00747 1/20 0.55
PRSS1 P07477 1/20 0.55
PRSS2 P07478 1/20 0.55
PRSS3 P35030 1/20 0.55
ST14 Q9Y5Y6 1/20 0.55
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
GAA P10253 3/20 0.49
MAPT P10636 2/20 0.49
GFER P55789 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
HPGD P15428 2/20 0.47
HTT P42858 2/20 0.47
GLA P06280 1/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19327630 1.00 HSD17B10 (0.59) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL19327668 1.00 HSD17B10 (0.59) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL19327640 1.00 HSD17B10 (0.59) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL19327631 1.00 HSD17B10 (0.59) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL1947748 0.89 HSD17B10 (0.63) HSD17B10LMNANPSR1NAMPTMEN1
SCHEMBL19327701 0.88 GLA (0.66) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL19327738 0.88 GLA (0.66) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL19327789 0.88 GLA (0.66) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL19327698 0.88 GLA (0.66) HSD17B10LMNANPSR1NAMPTF2
SCHEMBL19327736 0.88 GLA (0.66) HSD17B10LMNANPSR1NAMPTF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071458-B Triamide compounds and compositions comprising the same 美利肯公司 2021-12-10 CN disclosed
US-10844006-B2 Trisamide compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2020-11-24 US disclosed
US-20170260129-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME MILLIKEN & CO (US) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844006-B2 Trisamide compounds and compositions comprising the same TELO2, TERT, H1-2 HSD17B10 4254/4885LMNA 1125/4885NPSR1 1388/4885
US-20170260129-A1 TRISAMIDE COMPOUNDS AND COMPOSITIONS COMPRISING THE SAME TELO2, TERT, H1-2 HSD17B10 4254/4885LMNA 1125/4885NPSR1 1388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.