Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 12/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 12/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9694366 | 0.92 | KDM4E (0.53) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| Bromide SCHEMBL19211094 | 0.92 | KDM4E (0.53) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| Bromide SCHEMBL9029175 | 0.92 | KDM4E (0.53) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL29601881 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL9155741 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL9722985 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL29602006 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL29601298 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL29601334 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL29601800 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8409792-B2 | Color intermediate motion picture film | EAST KODAK COMPANY (US) | 2013-04-02 | — | — | US | disclosed |
| US-7998665-B2 | Color intermediate motion picture film | EASTMAN KODAK COMPANY (US) | 2011-08-16 | — | — | US | disclosed |
| US-20110136065-A1 | COLOR INTERMEDIATE MOTION PICTURE FILM | QUALEX INC. | 2011-06-09 | — | — | US | disclosed |
| US-20100167218-A1 | COLOR INTERMEDIATE MOTION PICTURE FILM | EASTMAN KODAK COMPANY | 2010-07-01 | — | — | US | disclosed |
| EP-0718679-B1 | Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements | EASTMAN KODAK CO (US) | 2006-02-15 | — | — | EP | disclosed |
| EP-0772079-B1 | Light-sensitive silber halide emulsions and processes for their preparation | EASTMAN KODAK CO (US) | 2002-12-11 | — | — | EP | disclosed |
| US-5792601-A | MODIFYING THE PERFORMANCE PROPERTIES OF THE HIGH CHLORIDE SILVER HALIDE EMULSION BY A COMBINATION OF SILVER BROMIDE ADDITION, IRIDIUM DOPANT INCORPORATION AND ANTIFOGGANT ADDITION | EASTMAN KODAK COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| US-5736310-A | SILVER IODOCHLORIDE GRAINS GROWN IN DISPERSING MEDIUM; EMPLOYING GRAINS AS SUBSTRATES FOR FURTHER GRAIN GROWTH | EASTMAN KODAK COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| US-5728516-A | Photographic print elements containing cubical grain silver iodochloride emulsions | EASTMAN KODAK COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5726005-A | Photographic print elements containing cubical grain silver iodochloride emulsions | EASTMAN KODAK COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| EP-0772079-A2 | Light-sensitive silber halide emulsions and processes for their preparation | EASTMAN KODAK COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0718676-A1 | Photographic print elements containing emulsions of enhanced speed and controlled minimum densities | EASTMAN KODAK COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| EP-0718679-A1 | Cubical silver iodochloride emulsions, processes for their preparation and photographic print elements | EASTMAN KODAK COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| EP-0397125-B1 | Silver halide emulsions having improved low intensity reciprocity characteristics and processes of preparing them | EASTMAN KODAK CO (US) | 1995-12-27 | — | — | EP | disclosed |
| EP-0617320-A2 | Tabular grain emulsions containing antifoggants and stabilizers | EASTMAN KODAK COMPANY (US) | 1994-09-28 | — | — | EP | disclosed |
| US-5320938-A | Occurs in the presence of iodide | EASTMAN KODAK COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-4997751-A | INCORPORATING IRIDIUM | EASTMAN KODAK COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0397125-A2 | Silver halide emulsions having improved low intensity reciprocity characteristics and processes of preparing them | EASTMAN KODAK COMPANY (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4146395-A | POISONING FIRST SILVER IMAGE, REVERSE SILVER IMAGE PATTERN USED AS REDOX CATALYST | EASTMAN KODAK COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4089685-A | DEVELOPING SILVER IMAGE FROM EXPOSED SILVER HALIDE PHOTOGRAPHIC ELEMENT, POISIONING, REDUCTION | EASTMAN KODAK COMPANY (US) | 1978-05-16 | — | — | US | disclosed |