Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19478728 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2USP2CASRRECQLGAA | |
| SCHEMBL22910970 | 0.86 | DPP7 (0.39) | DPP4DPP8 | |
| SCHEMBL23893372 | 0.85 | DPP7 (0.41) | ALDH1A1DPP4DPP8CTSK | |
| SCHEMBL317073 | 0.80 | DPP4 (0.44) | SMN1; SMN2RECQLGAAALDH1A1TSHR | |
| SCHEMBL317074 | 0.80 | DPP4 (0.44) | SMN1; SMN2RECQLGAAALDH1A1TSHR | |
| SCHEMBL2846938 | 0.79 | USP2 (0.46) | SMN1; SMN2USP2CASRRECQLGAA | |
| SCHEMBL2846932 | 0.79 | USP2 (0.46) | SMN1; SMN2USP2CASRRECQLGAA | |
| SCHEMBL14282734 | 0.78 | USP2 (0.44) | SMN1; SMN2USP2CASRRECQLGAA | |
| SCHEMBL956440 | 0.77 | P2RY12 (0.41) | DPP4DPP8 | |
| SCHEMBL956438 | 0.77 | P2RY12 (0.41) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220193249-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-O-) Units In A Ring | POLYTHERICS LIMITED (GB) | 2022-06-23 | — | — | US | disclosed |
| US-20190328893-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-0-) Units In A Ring | POLYTHERICS LIMITED (GB) | 2019-10-31 | — | — | US | disclosed |
| WO-2017178828-A1 | CONJUGATES AND CONJUGATING REAGENTS COMPRISING A LINKER THAT INCLUDES AT LEAST TWO (-CH2-CH2-0-) UNITS IN A RING | POLYTHERICS LIMITED (GB) | 2017-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190328893-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-0-) Units In A Ring | BCR, CD2BP2, LANCL1 | SMN1; SMN2 2898/4885USP2 263/4885CASR 4730/4885 |
| US-20220193249-A1 | Conjugates And Conjugating Reagents Comprising A Linker That Includes At Least Two (-CH2-CH2-O-) Units In A Ring | BCR, CD2BP2, LANCL1 | SMN1; SMN2 3092/4885USP2 239/4885CASR 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.