SCHEMBL2846932

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2846938	1.00	USP2 (0.46)	USP2SMN1; SMN2CTSLCTSBCTSD
	SCHEMBL19707910	0.91	MEN1 (0.46)	USP2SMN1; SMN2CTSLCTSBCTSD
	SCHEMBL6792312	0.87	DPP7 (0.46)	CTSKMEN1KMT2AGAATDP1
	SCHEMBL14282734	0.84	USP2 (0.44)	USP2SMN1; SMN2CTSLCTSBCTSD
	SCHEMBL951878	0.82	MEN1 (0.43)	SMN1; SMN2MEN1KMT2AGAARECQL
	SCHEMBL951877	0.82	MEN1 (0.43)	SMN1; SMN2MEN1KMT2AGAARECQL
	SCHEMBL2852709	0.82	CD274 (0.43)	USP2SMN1; SMN2CTSLCTSBCTSD
	SCHEMBL2852705	0.82	CD274 (0.43)	USP2SMN1; SMN2CTSLCTSBCTSD
	SCHEMBL13598863	0.81	MEN1 (0.54)	CTSKMEN1KMT2AGAATDP1
	SCHEMBL19478686	0.79	SMN1; SMN2 (0.51)	USP2SMN1; SMN2CTSLCTSBCTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.