SCHEMBL1948064

SCHEMBL1948064

CCC(C)(C)C(=O)Nc1cc(NC(=O)C(C)(C)C)cc(NC(=O)C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
GAA P10253 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CNR2 P34972 7/20 0.47
CNR1 P21554 6/20 0.47
NPSR1 Q6W5P4 1/20 0.46
MAPT P10636 2/20 0.45
BRD4 O60885 1/20 0.45
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950254 1.00 L3MBTL1 (0.55) L3MBTL1GAAMEN1KMT2ACNR2
SCHEMBL1948564 0.94 CNR2 (0.50) L3MBTL1GAAMEN1KMT2ACNR2
SCHEMBL28419749 0.90 NPSR1 (0.61) L3MBTL1CNR2NPSR1MAPTBRD4
SCHEMBL12226381 0.89 L3MBTL1 (0.73) L3MBTL1MEN1KMT2ANPSR1MAPT
SCHEMBL23441 0.85 L3MBTL1 (0.73) L3MBTL1GAAMEN1KMT2ANPSR1
SCHEMBL14134918 0.83 POLB (0.54) L3MBTL1MEN1KMT2ACNR2NPSR1
SCHEMBL1947974 0.82 HPGD (0.50) L3MBTL1GAAMEN1KMT2ACNR2
SCHEMBL22270330 0.82 CNR2 (0.46) L3MBTL1GAAMEN1KMT2ACNR2
SCHEMBL1948502 0.82 KMT2A (0.47) L3MBTL1GAAMEN1KMT2ACNR2
SCHEMBL13139911 0.82 HPGD (0.50) L3MBTL1GAAMEN1KMT2ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP claimed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US claimed
WO-2015021948-A1 AGENT FOR NUCLEATION OF POLYOLEFIN AND ELIMINATION OF FOULING IN A GAS PHASE POLYMERISATION REACTOR POLYMER INSTITUTE BRNO, SPOL. S.R.O. (CZ) 2015-02-19 WO claimed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP claimed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US claimed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US claimed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US claimed
JP-2006518402-A 2006-08-10 JP claimed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP claimed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO claimed
US-20200384678-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2020-12-10 US disclosed
EP-3715092-A1 DECORATIVE FILM AND METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE USING SAME Japan Polypropylene Corporation (JP) 2020-09-30 EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9732198-B2 Mono- and multi-layer blown films BASF SE (DE) 2017-08-15 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed
WO-2007068766-A1 MONO- AND MULTI-LAYER BLOWN FILMS CIBA HOLDING INC. (CH) 2007-06-21 WO disclosed
EP-1592738-A2 RESIN COMPOSITIONS Ciba SC Holding AG (CH) 2005-11-09 EP disclosed
WO-2004072168-A2 RESIN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-08-26 WO disclosed