Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1A1 | Q02108 | 5/20 | 0.46 |
| ▸ | GUCY1B1 | Q02153 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739532 | 0.78 | GUCY1A1 (0.48) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| SCHEMBL13738365 | 0.75 | GUCY1A1 (0.46) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| SCHEMBL14754744 | 0.73 | GUCY1A1 (0.51) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| SCHEMBL15693415 | 0.72 | GUCY1A1 (0.62) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| SCHEMBL13737905 | 0.71 | GUCY1A1 (0.67) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL13737969 | 0.71 | GUCY1A1 (0.66) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| SCHEMBL13738008 | 0.71 | GUCY1A1 (0.48) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| SCHEMBL20140419 | 0.70 | GUCY1A1 (0.37) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A | |
| SCHEMBL13738580 | 0.70 | PDE10A (0.40) | GUCY1A1GUCY1B1KCNH2ALDH1A1KDM4E | |
| SCHEMBL13738267 | 0.69 | GUCY1A1 (0.47) | GUCY1A1GUCY1B1KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751106-B1 | SUBSTITUTED ANNELLATED PYRIMIDINE AND THE USE THEREOF | BAYER IP GMBH (DE) | 2017-10-18 | — | — | EP | disclosed |