Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM6A | O15550 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16155571 | 0.81 | MYC (0.60) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL29442955 | 0.76 | KDM4E (0.63) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL932828 | 0.76 | KDM4E (0.63) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10560254 | 0.74 | KDM4E (0.61) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL27775136 | 0.74 | MYC (0.60) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL17746081 | 0.72 | MYC (0.58) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL7090852 | 0.71 | MYC (0.57) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL15714407 | 0.71 | MYC (1.00) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL29551359 | 0.71 | MYC (0.57) | MYCKDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL30477850 | 0.71 | KMT2A (0.70) | MYCKDM4ETDP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442965-B1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2021-05-26 | — | — | EP | disclosed |
| WO-2017178344-A1 | NOVEL N-[(HETEROARYLOXY)PROPANYL]HETEROARYL CARBOXAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |