Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGAV | P06756 | 3/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15020060 | 1.00 | PPARG (0.48) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL15020061 | 1.00 | PPARG (0.48) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL16306092 | 0.89 | PLG (0.44) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL15019521 | 0.88 | ITGB3 (0.54) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL22449180 | 0.88 | ITGB3 (0.54) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL15037062 | 0.88 | ITGB3 (0.54) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL15019519 | 0.88 | ITGB3 (0.54) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL15037069 | 0.88 | ITGB3 (0.54) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL15037061 | 0.88 | ITGB3 (0.54) | PPARGPPARAITGB3ITGAVITGB1 | |
| SCHEMBL15092133 | 0.88 | ITGB3 (0.54) | PPARGPPARAITGB3ITGAVITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |