⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356230 | 0.74 | — | — | |
| SCHEMBL2360119 | 0.72 | — | — | |
| SCHEMBL5704609 | 0.70 | — | — | |
| SCHEMBL15765095 | 0.69 | HCAR2 (0.48) | — | |
| SCHEMBL26932947 | 0.68 | TAAR1 (0.34) | — | |
| SCHEMBL27390227 | 0.68 | HCAR2 (0.32) | — | |
| SCHEMBL51391 | 0.67 | — | — | |
| SCHEMBL2310170 | 0.67 | TAAR1 (0.33) | — | |
| SCHEMBL9113080 | 0.66 | — | — | |
| SCHEMBL28565958 | 0.65 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 435 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250157-B | Method for synthesizing N- [2- (2-arylbenzothiazole) ] -amide under catalysis of rhodium | 江西师范大学 | 2021-12-21 | — | — | CN | claimed |
| CN-111100092-A | Method for direct amination of thioamide-oriented aromatic hydrocarbon carbon-hydrogen | 宁夏大学 | 2020-05-05 | — | — | CN | claimed |
| CN-107108600-A | It is used as the heteroarylalkylenyl aryl sultam derivative of RORc conditioning agents | 豪夫迈·罗氏有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-103539753-B | A kind of synthetic method of the isoxazole carboxylic acid of 3 substitution 4 | 上海药明康德新药开发有限公司 | 2017-06-23 | — | — | CN | claimed |
| US-8367719-B2 | Aryl-substituted bridged or fused diamines as modulators of leukotriene A4 hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2013-02-05 | — | — | US | claimed |
| CN-102812011-A | [1,5] -diazacyclo-octatetraene derivative | MELLITECH | 2012-12-05 | — | — | CN | claimed |
| EP-2501685-A1 | [1,5]-DIAZOCIN DERIVATIVES | Mellitech (FR) | 2012-09-26 | — | — | EP | claimed |
| US-20120225892-A1 | [1,5]-Diazocin Derivatives | MELLITECH (FR) | 2012-09-06 | — | — | US | claimed |
| EP-1817036-B1 | MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMA (US) | 2012-07-04 | — | — | EP | claimed |
| US-20110263639-A1 | Aryl-substituted bridged or fused diamines as modulators of leukotriene A4 hydrolase | Janseen Pharmaceutical NV | 2011-10-27 | — | — | US | claimed |
| CN-1072222-C | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | UPJOHN CO (US) | 2001-10-03 | — | — | CN | claimed |
| US-6166056-A | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | PHARMACIA (US) | 2000-12-26 | — | — | US | claimed |
| US-5922707-A | Oxazolidinone antibacterial agent with tricyclic substituents | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-13 | — | — | US | claimed |
| EP-0874852-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENT WITH TRICYCLIC SUBSTITUENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-11-04 | — | — | EP | claimed |
| CN-1197457-A | Phenyloxazolidinones having a C-C bond to a 4-8 membered heterocyclic ring | UPJOHN CO (US) | 1998-10-28 | — | — | CN | claimed |
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | claimed |
| WO-1997019089-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENT WITH TRICYCLIC SUBSTITUENTS | PHARMACIA & UPJOHN COMPANY (US) | 1997-05-29 | — | — | WO | claimed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | claimed |
| US-5017212-A | For rice paddies | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-05-21 | — | — | US | claimed |
| EP-0302491-A1 | 5-Formyl-isoxazoles | BASF Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | claimed |