Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19483138 | 1.00 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL17658911 | 1.00 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL6434347 | 0.77 | — | — | |
| SCHEMBL29247929 | 0.76 | — | — | |
| SCHEMBL5027041 | 0.75 | — | — | |
| SCHEMBL6434185 | 0.73 | LMNA (0.38) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL10540575 | 0.72 | MEN1 (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6433810 | 0.71 | — | — | |
| SCHEMBL12251749 | 0.71 | — | — | |
| SCHEMBL880845 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298402-A1 | SELF-LABELING NUCLEIC ACIDS AND METHODS OF USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-10-19 | — | — | US | disclosed |