Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26767237 | 0.81 | AR (0.39) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL11116978 | 0.79 | ALDH1A1 (0.44) | ARHTTHIF1AALDH1A1LMNA | |
| SCHEMBL19459671 | 0.79 | AR (0.66) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL19460183 | 0.79 | AR (0.66) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL26638246 | 0.79 | AR (0.66) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL19459796 | 0.79 | AR (0.66) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL19484398 | 0.79 | AR (0.66) | ARHTTHIF1AKDM4EKMT2A | |
| SCHEMBL19460127 | 0.79 | AR (0.66) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL19460233 | 0.79 | AR (0.66) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL19482517 | 0.79 | AR (0.62) | ARHTTHIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017177307-A1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2017-10-19 | — | — | WO | disclosed |