Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19479367 | 1.00 | HPGD (0.47) | HPGDMAPK1LMNAMAPTSIGMAR1 | |
| SCHEMBL2608849 | 0.82 | HPGD (0.50) | HPGDMAPK1LMNAMAPTTSHR | |
| SCHEMBL16592084 | 0.81 | HPGD (0.50) | HPGDMAPK1LMNAMAPTTSHR | |
| SCHEMBL19480710 | 0.81 | SIGMAR1 (0.42) | HPGDLMNAMAPTSIGMAR1ADRA2C | |
| SCHEMBL19484271 | 0.81 | ACACB (0.40) | LMNAACACBL3MBTL1TRPV3 | |
| SCHEMBL19484272 | 0.81 | ACACB (0.40) | LMNAACACBL3MBTL1TRPV3 | |
| SCHEMBL19480925 | 0.79 | HPGD (0.48) | HPGDMAPK1LMNAMAPTTSHR | |
| SCHEMBL19480926 | 0.79 | HPGD (0.48) | HPGDMAPK1LMNAMAPTTSHR | |
| SCHEMBL19480711 | 0.78 | SIGMAR1 (0.35) | LMNAMAPTSIGMAR1ADRA2CHTR2A | |
| SCHEMBL19480704 | 0.78 | SIGMAR1 (0.35) | LMNAMAPTSIGMAR1ADRA2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442958-B1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |
| WO-2017178340-A1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |