Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 19/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19485567 | 1.00 | LCAT (0.65) | LCATDRD2DRD3 | |
| SCHEMBL18138567 | 0.91 | LCAT (0.77) | LCAT | |
| SCHEMBL18138637 | 0.91 | LCAT (0.77) | LCAT | |
| SCHEMBL18138552 | 0.91 | LCAT (0.77) | LCAT | |
| SCHEMBL18138638 | 0.91 | LCAT (0.77) | LCAT | |
| SCHEMBL18138564 | 0.91 | LCAT (0.77) | LCAT | |
| SCHEMBL19485568 | 0.82 | LCAT (0.62) | LCAT | |
| SCHEMBL19485093 | 0.79 | LCAT (0.63) | LCAT | |
| SCHEMBL16648725 | 0.79 | LCAT (0.74) | LCAT | |
| SCHEMBL19485564 | 0.78 | LCAT (0.62) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796709-B2 | 5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |