Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 16/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18138653 | 0.89 | LCAT (0.75) | LCAT | |
| SCHEMBL18138550 | 0.89 | LCAT (0.75) | LCAT | |
| SCHEMBL18138652 | 0.89 | LCAT (0.75) | LCAT | |
| SCHEMBL19485568 | 0.81 | LCAT (0.62) | LCAT | |
| SCHEMBL19485091 | 0.81 | LCAT (0.63) | LCATMAPT | |
| SCHEMBL19485567 | 0.78 | LCAT (0.65) | LCAT | |
| SCHEMBL19485396 | 0.78 | LCAT (0.65) | LCAT | |
| SCHEMBL19485388 | 0.78 | LCAT (0.49) | LCATADRB1FFAR4HRH3 | |
| SCHEMBL19485369 | 0.77 | LCAT (0.47) | LCAT | |
| SCHEMBL16648617 | 0.77 | LCAT (0.73) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796709-B2 | 5-hydroxy-4-(trifluoromethyl)pyrazolopyridine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |