Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23046348 | 0.83 | SLC6A4 (0.37) | PARP10CA1CA2CA9SLC6A4 | |
| SCHEMBL18260812 | 0.83 | CA1 (0.38) | PARP10CA1CA2CA9SLC6A4 | |
| SCHEMBL28772088 | 0.79 | PARP10 (0.41) | PARP10CA1CA2CA9SLC6A4 | |
| SCHEMBL28556902 | 0.74 | PARP10 (0.43) | PARP10CA1CA2CA9ALDH1A1 | |
| SCHEMBL256381 | 0.73 | ALDH1A3 (0.52) | PARP10CA1CA2CA9ALDH1A1 | |
| SCHEMBL2771834 | 0.72 | PARP10 (0.36) | PARP10CA1CA2CA9SLC6A4 | |
| SCHEMBL3399534 | 0.71 | KMT2A (0.38) | PARP10CA1CA2CA9ALDH1A1 | |
| SCHEMBL18260758 | 0.69 | SLC6A4 (0.39) | PARP10CA1CA2CA9SLC6A4 | |
| SCHEMBL15300858 | 0.69 | SLC6A4 (0.39) | SLC6A4KMT2AAPPPOLB | |
| SCHEMBL28698394 | 0.68 | ALDH1A3 (0.47) | PARP10CA9ALDH1A1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796683-B2 | Tetrasubstituted alkene compounds and their use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-10-24 | — | — | US | disclosed |
| US-9796683-B2 | Tetrasubstituted alkene compounds and their use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-10-24 | — | — | US | disclosed |