SCHEMBL19486009

COc1ccc(NC(=O)[C@H](CCCCN)NC(=O)c2cc(NC(=O)[C@H](CCCCN)NC(=O)c3cc(NC(=O)[C@H](CCCCCN)NC(=O)c4cc(NC(=O)[C@@H](N)CCCC(=O)O)ccc4OC)ccc3OC)ccc2OC)cc1C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MMP2	P08253	5/20	0.44

▸	SUV39H2	Q9H5I1	2/20	0.43

▸	ERAP2	Q6P179	6/20	0.42

▸	LNPEP	Q9UIQ6	4/20	0.42

▸	ERAP1	Q9NZ08	3/20	0.42

▸	LTA4H	P09960	1/20	0.40

▸	TSHR	P16473	1/20	0.39

▸	S1PR1	P21453	2/20	0.39

▸	S1PR3	Q99500	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19944937	0.97	MMP2 (0.48)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL12515485	0.96	MMP2 (0.49)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL12515481	0.96	MMP2 (0.49)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL12515487	0.96	MMP2 (0.49)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL12515474	0.95	MMP2 (0.47)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL19445788	0.95	MMP2 (0.47)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL10261754	0.95	ERAP2 (0.46)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL19486133	0.94	ERAP2 (0.45)	MMP2SUV39H2ERAP2LNPEPERAP1
SCHEMBL17949785	0.94	MMP2 (0.49)	MMP2SUV39H2ERAP2LNPEPERAP1
Delparantag SCHEMBL10267622	0.94	ERAP2 (0.47)	MMP2SUV39H2ERAP2LNPEPERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9795575-B2	Compounds for use in treatment of mucositis	INNOVATION PHARMACEUTICALS INC. (US)	2017-10-24	—	—	US	disclosed