SCHEMBL1948601

SCHEMBL1948601

CC(=O)NC[C@H]1CN(c2ccc(N3CC[C@@H](n4ncnn4)C3)c(F)c2)C(=O)O1

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.65
MAOB P27338 4/20 0.65
PTGS1 P23219 2/20 0.65
SDHA P31040 2/20 0.65
LMNA P02545 1/20 0.65
CALML3 P27482 1/20 0.65
F10 P00742 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1952356 1.00 MAOA (0.65) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1952354 1.00 MAOA (0.65) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1951689 1.00 MAOA (0.65) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4168224 0.96 MAOB (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4168218 0.96 MAOB (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1951701 0.90 MAOA (0.69) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1950877 0.90 MAOA (0.69) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1950875 0.90 MAOA (0.69) MAOAMAOBPTGS1SDHALMNA
SCHEMBL1952198 0.90 MAOA (0.69) MAOAMAOBPTGS1SDHALMNA
SCHEMBL3654388 0.89 MAOA (0.51) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2324016-B1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INT (ES) 2012-04-25 EP claimed
US-20110136829-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2011-06-09 US claimed
EP-2141162-A1 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2010-01-06 EP claimed
EP-2324016-B1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INT (ES) 2012-04-25 EP disclosed
US-20110136829-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2011-06-09 US disclosed
EP-2141162-A1 3-(n-heterocyclyl)-pyrrolidinyl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2010-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136829-A1 3-(N-HETEROCYCLYL)-PYRROLIDINYL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS OXA1L, MRPL21, RPL5 MAOA 1983/4885MAOB 1397/4885PTGS1 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.