SCHEMBL19486285

SCHEMBL19486285

CC#CC(CC)c1ccc(OCc2ccc3scc(-c4cc(OCCOC)cnc4C)c3c2)cc1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19436277 0.91 FFAR1 (0.78) FFAR1
SCHEMBL17669646 0.90 FFAR1 (1.00) FFAR1
SCHEMBL17669610 0.90 FFAR1 (1.00) FFAR1
SCHEMBL19436118 0.90 FFAR1 (0.89) FFAR1
SCHEMBL19436203 0.89 FFAR1 (0.87) FFAR1
SCHEMBL19436062 0.88 FFAR1 (0.78) FFAR1
SCHEMBL19436066 0.88 FFAR1 (0.78) FFAR1
SCHEMBL19479933 0.86 FFAR1 (0.77) FFAR1
SCHEMBL19479931 0.86 FFAR1 (0.77) FFAR1
SCHEMBL19486338 0.83 FFAR1 (0.86) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017180457-A1 GPR40 AGONISTS IN ANTI-DIABETIC DRUG COMBINATIONS JANSSEN PHARMACEUTICA NV (BE) 2017-10-19 WO disclosed