SCHEMBL19486338

SCHEMBL19486338

C#C[C@@H](CC(=O)O)c1ccc(OCc2ccc3scc(-c4cc(OCCOC)cnc4C)c3c2)cc1

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17669646 0.92 FFAR1 (1.00) FFAR1
SCHEMBL17669610 0.92 FFAR1 (1.00) FFAR1
SCHEMBL19486339 0.89 FFAR1 (0.80) FFAR1
SCHEMBL19436118 0.86 FFAR1 (0.89) FFAR1
SCHEMBL19436203 0.86 FFAR1 (0.87) FFAR1
SCHEMBL17669380 0.84 FFAR1 (1.00) FFAR1
SCHEMBL17669265 0.84 FFAR1 (1.00) FFAR1
SCHEMBL17669379 0.84 FFAR1 (1.00) FFAR1
SCHEMBL17669334 0.84 FFAR1 (1.00) FFAR1
SCHEMBL19486285 0.83 FFAR1 (0.81) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017180457-A1 GPR40 AGONISTS IN ANTI-DIABETIC DRUG COMBINATIONS JANSSEN PHARMACEUTICA NV (BE) 2017-10-19 WO disclosed