Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.55 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6138768 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL20681645 | 1.00 | ALDH1A1 (0.62) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL28475084 | 0.97 | ALDH1A1 (0.59) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL10702938 | 0.94 | ALDH1A1 (0.56) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL64593 | 0.93 | ALDH1A1 (0.68) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Acetic Acid SCHEMBL9717378 | 0.91 | ALDH1A1 (0.68) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Benzene SCHEMBL11159553 | 0.90 | ALDH1A1 (0.59) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| SCHEMBL29446779 | 0.90 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Ammonia Solution, Strong SCHEMBL5679172 | 0.90 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL26134181 | 0.90 | ALDH1A1 (0.65) | ALDH1A1TSHRCHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996927-A | Pyrimido [5,4-d ] pyrimidine derivatives and combinations with adenosine receptor antagonists as ENT inhibitors for the treatment of cancer | ITEOS比利时公司 | 2023-04-21 | — | — | CN | claimed |
| CN-115521175-A | Special nutrient solution for vegetables | 珠海市现代农业发展中心(珠海市金湾区台湾农民创业园管理委员会、珠海市农渔业科研与推广中心) | 2022-12-27 | — | — | CN | claimed |
| EP-0727491-B1 | Enzymatic synthesis of soluble phosphatides from phospholipids | LIPOSOME CO INC (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0727491-A1 | Enzymatic synthesis of soluble phosphatides from phospholipids | THE LIPOSOME COMPANY, INC. (US) | 1996-08-21 | — | — | EP | claimed |
| EP-0528834-A4 | ENZYMATIC SYNTHESIS OF SOLUBLE PHOSPHATIDES FROM PHOSPHOLIPIDS | — | 1993-06-02 | — | — | EP | claimed |
| EP-0528834-A1 | ENZYMATIC SYNTHESIS OF SOLUBLE PHOSPHATIDES FROM PHOSPHOLIPIDS. | LIPOSOME CO INC (US) | 1993-03-03 | — | — | EP | claimed |
| US-5188951-A | Reacting phospholipid with primary alcohol in presence of enzyme catalyst in divalent cationic solution to form divalent salt, reacting formed salt with monovalent cationic salt to form monovalent salt | THE LIPOSOME COMPANY, INC. (US) | 1993-02-23 | — | — | US | claimed |
| WO-1991016444-A1 | ENZYMATIC SYNTHESIS OF SOLUBLE PHOSPHATIDES FROM PHOSPHOLIPIDS | THE LIPOSOME COMPANY, INC. (US) | 1991-10-31 | — | — | WO | claimed |
| EP-4259869-B1 | TEXTILE SHEET MATERIAL | WACKER CHEMIE AG (DE) | 2024-07-03 | — | — | EP | disclosed |
| US-20240026583-A1 | TEXTILE SHEET MATERIAL | WACKER CHEMIE AG (DE) | 2024-01-25 | — | — | US | disclosed |
| EP-4259869-A1 | TEXTILE SHEET MATERIAL | Wacker Chemie AG (DE) | 2023-10-18 | — | — | EP | disclosed |
| CN-103554138-B | A kind of have material of organic field effect tube character and preparation method thereof | LANZHOU UNIVERSITY (CN) | 2016-02-17 | — | — | CN | disclosed |
| US-8642029-B2 | Transiently buffered Lactobacillus preparations and use thereof | OSEL, INC. (US) | 2014-02-04 | — | — | US | disclosed |
| US-8329447-B2 | Strain of Lactobacillus crispatus | OSEL, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110135615-A1 | TRANSIENTLY BUFFERED LACTOBACILLUS PREPARATIONS AND USE THEREOF | OSEL, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20100151026-A1 | NOVEL STRAIN OF LACTOBACILLUS CRISPATUS | OSEL, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2009123982-A2 | TRANSIENTLY BUFFERED LACTOBACILLUS PREPARATIONS AND USE THEREOF | OSEL, INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| EP-0630962-A1 | Builder system suitable for cleaning agent | SARA LEE/DE N.V. (NL) | 1994-12-28 | — | — | EP | disclosed |
| EP-0388389-A2 | Improved detergent compositions | MONSANTO EUROPE S.A./N.V. (BE) | 1990-09-19 | — | — | EP | disclosed |