Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10094627 | 0.79 | NPSR1 (0.51) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL19477820 | 0.79 | NPSR1 (0.51) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL29463926 | 0.79 | NPSR1 (0.51) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL20040419 | 0.79 | TSHR (0.66) | KMT2AMEN1ALDH1A1TSHRLCK | |
| SCHEMBL10094657 | 0.78 | NPSR1 (0.50) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL10094632 | 0.78 | KMT2A (0.69) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL10094695 | 0.77 | NPSR1 (0.49) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL10094747 | 0.76 | MAPK1 (0.52) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL10094699 | 0.74 | KMT2A (0.56) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL10094735 | 0.74 | MEN1 (0.47) | NPSR1KMT2AMEN1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178864-A1 | SEVEN-MEMBERED RING COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-10-19 | — | — | WO | disclosed |