Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15605425 | 0.89 | TSHR (0.68) | TSHRALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL19486136 | 0.85 | TSHR (0.48) | TSHRALDH1A1KMT2AL3MBTL1HTT | |
| SCHEMBL22513715 | 0.80 | HSD17B10 (0.42) | TSHRALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL15605424 | 0.80 | TSHR (1.00) | TSHRALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL19486457 | 0.79 | NPSR1 (0.49) | TSHRALDH1A1KMT2AHTTMAPK1 | |
| SCHEMBL15605428 | 0.79 | TSHR (0.55) | TSHRALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL804994 | 0.77 | TSHR (0.70) | TSHRALDH1A1LMNAL3MBTL1HTT | |
| SCHEMBL19486106 | 0.77 | TSHR (0.70) | TSHRALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL20040513 | 0.77 | TSHR (0.70) | TSHRALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL804812 | 0.75 | TSHR (0.68) | TSHRALDH1A1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318566-A1 | AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2018-05-09 | — | — | EP | disclosed |
| EP-3053918-B1 | 2-carbazole substituted benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |