Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | CDC7 | O00311 | 9/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.36 |
| ▸ | CDK2 | P24941 | 5/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.36 |
| ▸ | PIM1 | P11309 | 4/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12423427 | 0.90 | SCN10A (0.54) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL12798759 | 0.83 | SCN10A (0.52) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL24463096 | 0.82 | NPC1 (0.42) | — | |
| SCHEMBL12943567 | 0.79 | SCN10A (0.48) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL12684295 | 0.78 | SCN10A (0.59) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL19488467 | 0.78 | SCN10A (0.59) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL12509313 | 0.78 | SCN10A (0.58) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL16938792 | 0.77 | SCN10A (0.43) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL9605019 | 0.77 | SCN10A (0.56) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL1645792 | 0.77 | SCN10A (0.56) | SCN10APARP1CDC7CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |