Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.55 |
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | AHCY | P23526 | 2/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936475 | 0.86 | EHMT1 (0.74) | SMN1; SMN2ADORA3EHMT1SLC29A1RXFP1 | |
| SCHEMBL8671033 | 0.86 | EHMT1 (0.74) | SMN1; SMN2ADORA3EHMT1SLC29A1RXFP1 | |
| SCHEMBL8671037 | 0.86 | EHMT1 (0.74) | SMN1; SMN2ADORA3EHMT1SLC29A1RXFP1 | |
| SCHEMBL26294910 | 0.84 | SMN1; SMN2 (0.67) | TP53SMN1; SMN2ADORA3EHMT1SLC29A1 | |
| SCHEMBL1637468 | 0.83 | EHMT1 (0.76) | SMN1; SMN2ADORA3EHMT1SLC29A1RXFP1 | |
| SCHEMBL9231760 | 0.83 | EHMT1 (0.76) | SMN1; SMN2ADORA3EHMT1SLC29A1RXFP1 | |
| SCHEMBL19488388 | 0.83 | RXFP1 (0.52) | TP53SMN1; SMN2ADORA3EHMT1SLC29A1 | |
| SCHEMBL21192264 | 0.83 | SLC29A1 (0.62) | TP53SMN1; SMN2ADORA3SLC29A1 | |
| SCHEMBL19488390 | 0.83 | SLC29A1 (0.62) | TP53SMN1; SMN2ADORA3SLC29A1 | |
| SCHEMBL1920531 | 0.82 | EHMT1 (0.74) | SMN1; SMN2ADORA3EHMT1SLC29A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017180981-A1 | NOVEL NUCLEOSIDE ANALOGS AND USE THEREOF IN THERAPEUTIC TREATMENT | CORNELL UNIVERSITY (US) | 2017-10-19 | — | — | WO | disclosed |