Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.32 |
| ▸ | WNT1 | P04628 | 3/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19488871 | 0.91 | DHODH (0.40) | DHODHATRSCN3ASCN9ABRAF | |
| SCHEMBL12405016 | 0.80 | DHODH (0.39) | DHODHATRGSK3BDYRK1AWNT1 | |
| SCHEMBL19488545 | 0.80 | DHODH (0.36) | DHODHATRGSK3BDYRK1AWNT1 | |
| SCHEMBL19488335 | 0.72 | DHODH (0.32) | DHODHTP53MAPTTHRBSMN1; SMN2 | |
| SCHEMBL12403441 | 0.71 | PRCP (0.37) | — | |
| SCHEMBL19488875 | 0.71 | DHODH (0.35) | DHODHATRGSK3BDYRK1AWNT1 | |
| SCHEMBL12403445 | 0.70 | SCN3A (0.37) | DHODHATRGSK3BDYRK1AWNT1 | |
| SCHEMBL19488330 | 0.70 | DHODH (0.32) | DHODH | |
| SCHEMBL19488872 | 0.69 | SCN3A (0.43) | DHODHGSK3BDYRK1AWNT1SCN3A | |
| SCHEMBL24731265 | 0.69 | PSMB8 (0.43) | DHODHSCN3ASCN9ABRAFPSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |