Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16572630 | 0.90 | SCN10A (0.51) | SCN10ADGAT1NPC1RAB9ASSTR3 | |
| SCHEMBL16405116 | 0.90 | SCN10A (0.51) | SCN10ADGAT1NPC1RAB9ASSTR3 | |
| SCHEMBL10144768 | 0.90 | SCN10A (0.51) | SCN10ADGAT1NPC1RAB9ASSTR3 | |
| SCHEMBL19488818 | 0.87 | SCN10A (0.41) | SCN10ANPY5R | |
| SCHEMBL19488496 | 0.81 | SCN10A (0.43) | SCN10ANPC1RAB9A | |
| SCHEMBL19488796 | 0.80 | SCN10A (0.45) | SCN10ANPC1RAB9ANPY5R | |
| SCHEMBL882760 | 0.80 | MAPK13 (0.41) | SCN10ASSTR3NPY5RKCNH2 | |
| SCHEMBL15388617 | 0.79 | SCN10A (0.45) | SCN10ADGAT1NPC1RAB9ANPY5R | |
| SCHEMBL15388620 | 0.79 | SCN10A (0.45) | SCN10ADGAT1NPC1RAB9ANPY5R | |
| SCHEMBL13192596 | 0.79 | SCN10A (0.56) | SCN10ANPC1RAB9ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |