Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10201776 | 0.91 | SCN10A (0.53) | SCN10APARP1NPC1RAB9ANPY5R | |
| SCHEMBL19488500 | 0.83 | SCN10A (0.48) | SCN10APARP1NPC1RAB9ANPY5R | |
| SCHEMBL19488795 | 0.80 | SCN10A (0.45) | SCN10APARP1NPC1RAB9ANPY5R | |
| SCHEMBL10201770 | 0.80 | SCN10A (0.41) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL19488602 | 0.80 | SCN10A (0.42) | SCN10ANPC1RAB9ANPY5R | |
| SCHEMBL19488496 | 0.79 | SCN10A (0.43) | SCN10ANPC1RAB9A | |
| SCHEMBL10200243 | 0.77 | SCN10A (0.45) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL12404403 | 0.77 | SCN10A (0.56) | SCN10APARP1NPC1RAB9ANPY5R | |
| SCHEMBL19488592 | 0.77 | SCN10A (0.41) | SCN10A | |
| SCHEMBL15045647 | 0.76 | SCN10A (0.54) | SCN10APARP1NPC1RAB9ACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |