Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800131 | 0.82 | SIRT6 (0.52) | FOLH1GSRSIRT6SIRT1SLC6A5 | |
| SCHEMBL29233135 | 0.81 | FOLH1 (0.37) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL168589 | 0.79 | FOLH1 (0.56) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL8291018 | 0.79 | SIRT6 (0.44) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL165084 | 0.79 | FOLH1 (0.56) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL10442084 | 0.79 | SIRT6 (0.44) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL164121 | 0.79 | FOLH1 (0.56) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL13416824 | 0.79 | FOLH1 (0.43) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL1262904 | 0.79 | FOLH1 (0.43) | FOLH1GSRSIRT6SIRT1RNPEP | |
| SCHEMBL2628440 | 0.79 | SIRT6 (0.44) | FOLH1GSRSIRT6SIRT1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934568-B1 | DUAL GLP1/GIP OR TRIGONAL GLP1/GIP/GLUCAGON AGONISTS | SANOFI SA (FR) | 2017-10-18 | — | — | EP | disclosed |