Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | WNT1 | P04628 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403445 | 0.89 | SCN3A (0.37) | SCN3ASCN9ADHODHGSK3BDYRK1A | |
| SCHEMBL19488327 | 0.85 | DHODH (0.35) | SCN3ASCN9ADHODHGSK3BDYRK1A | |
| SCHEMBL19488875 | 0.80 | DHODH (0.35) | SCN3ASCN9ADHODHGSK3BDYRK1A | |
| SCHEMBL12405016 | 0.78 | DHODH (0.39) | SCN3ASCN9ADHODHGSK3BDYRK1A | |
| SCHEMBL12403439 | 0.77 | SCN3A (0.47) | SCN3ASCN9ADHODHGSK3BDYRK1A | |
| SCHEMBL10201555 | 0.76 | DHODH (0.43) | SCN3ASCN9ADHODHPSMB8IKBKB | |
| SCHEMBL12403437 | 0.76 | DHODH (0.43) | SCN3ASCN9ADHODHPSMB8IKBKB | |
| SCHEMBL12406273 | 0.73 | PTGES (0.38) | SCN3ASCN9ADHODHGSK3BDYRK1A | |
| SCHEMBL19488855 | 0.73 | USP30 (0.40) | JAK2 | |
| SCHEMBL19488330 | 0.72 | DHODH (0.32) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601188-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-10-18 | — | — | EP | disclosed |