Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.47 |
| ▸ | CTSK | P43235 | 10/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149842 | 0.85 | ACACB (0.49) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL8172182 | 0.85 | ACACB (0.49) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL23224313 | 0.85 | ACACB (0.49) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL22506510 | 0.85 | CTSS (0.44) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL22506384 | 0.85 | CTSS (0.44) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL22506385 | 0.85 | CTSS (0.44) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL11852061 | 0.83 | CTSS (0.45) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL3645286 | 0.83 | CTSS (0.57) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL20470212 | 0.83 | CTSS (0.45) | CTSSCTSKCTSLCTSBTRPA1 | |
| SCHEMBL23200865 | 0.83 | CTSS (0.54) | CTSSCTSKCTSLCTSBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178350-A1 | 1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONES AND 1,5-DIHYDRO-4H-PYRAZOLO[4,3-C]PYRIDIN-4-ONES AS PDE1 INHIBITORS | H. LUNDBECK A/S (DK) | 2017-10-19 | — | — | WO | disclosed |