Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458946 | 0.85 | TDP1 (0.68) | TDP1RXRA | |
| SCHEMBL30631773 | 0.85 | TDP1 (0.68) | TDP1RXRA | |
| SCHEMBL4447832 | 0.74 | TDP1 (0.74) | TDP1RXRA | |
| SCHEMBL20976466 | 0.72 | TDP1 (0.59) | TDP1RXRA | |
| SCHEMBL26843469 | 0.71 | TDP1 (0.75) | TDP1RXRA | |
| SCHEMBL20944815 | 0.71 | ALDH1A1 (0.53) | TDP1RXRA | |
| SCHEMBL30631772 | 0.71 | ALDH1A1 (0.53) | TDP1RXRA | |
| SCHEMBL20944796 | 0.70 | TDP1 (0.76) | TDP1RXRA | |
| SCHEMBL2604424 | 0.70 | TDP1 (0.83) | TDP1RXRA | |
| SCHEMBL16312049 | 0.70 | TDP1 (0.70) | TDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796753-B2 | N-substituted indenoisoquinolines and syntheses thereof | PURDUE RESEARCH FOUNDATION (US) | 2017-10-24 | — | — | US | disclosed |