Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61248 | 0.93 | KDM1A (0.36) | DRD2DRD4KDM1ACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL9099409 | 0.91 | KDM1A (0.35) | DRD2DRD4KDM1ACYP11B1CYP11B2 | |
| SCHEMBL9222380 | 0.85 | DRD2 (0.33) | DRD2DRD4CYP11B1CYP11B2 | |
| SCHEMBL8572177 | 0.78 | — | — | |
| SCHEMBL7204963 | 0.77 | KDM1A (0.38) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL1924092 | 0.76 | CYP19A1 (0.34) | DRD2DRD4CYP11B1CYP11B2 | |
| SCHEMBL2074643 | 0.74 | KDM1A (0.40) | KDM1A | |
| SCHEMBL6355473 | 0.74 | CYP11B1 (0.35) | KDM1ACYP11B1CYP11B2 | |
| SCHEMBL10493942 | 0.71 | KDM1A (0.31) | KDM1A | |
| SCHEMBL616008 | 0.71 | KDM1A (0.34) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110137060-A1 | PREPARATION OF ANSA METALLOCENE COMPOUNDS | BASELL POLYOLEFIN GMBH (DE) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110137060-A1 | PREPARATION OF ANSA METALLOCENE COMPOUNDS | NCL, ARSA, NASP | DRD2 4049/4885DRD4 2655/4885KDM1A 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.