Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613524 | 0.89 | BTK (0.66) | BTKKITFLT3LCKLYN | |
| SCHEMBL15613517 | 0.89 | BTK (0.64) | BTKKITFLT3LCKLYN | |
| SCHEMBL15613473 | 0.85 | BTK (0.56) | BTKLCKLYNEGFRITK | |
| SCHEMBL15613516 | 0.80 | NUDT14 (0.62) | BTKEGFR | |
| SCHEMBL16886149 | 0.79 | BTK (0.69) | BTKKITFLT3LCKLYN | |
| SCHEMBL16886150 | 0.79 | BTK (0.67) | BTKKITFLT3LCKLYN | |
| SCHEMBL24827796 | 0.78 | BTK (0.74) | BTKFLT3LCKLYNEGFR | |
| SCHEMBL23409076 | 0.78 | BTK (0.74) | BTKFLT3LCKLYNEGFR | |
| SCHEMBL15613695 | 0.78 | BTK (0.79) | BTKFLT3LCKLYNEGFR | |
| SCHEMBL15613691 | 0.77 | BTK (0.66) | BTKKITFLT3LCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |