Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 16/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768157 | 0.86 | MAPK1 (0.41) | — | |
| SCHEMBL20768155 | 0.86 | MAPK1 (0.41) | — | |
| SCHEMBL20768140 | 0.77 | BRD4 (0.41) | — | |
| SCHEMBL19492620 | 0.77 | BRD4 (0.41) | — | |
| SCHEMBL19492619 | 0.75 | KCNH2 (0.33) | KDM4C | |
| SCHEMBL20768124 | 0.75 | MAPK1 (0.40) | — | |
| SCHEMBL19492795 | 0.75 | MAPK1 (0.40) | — | |
| SCHEMBL19492794 | 0.74 | KDM4C (0.32) | KDM4CMAPTKDM6B | |
| SCHEMBL19464216 | 0.73 | BRD4 (0.40) | — | |
| SCHEMBL19464218 | 0.73 | BRD4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017178416-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2017-10-19 | — | — | WO | disclosed |